4-(3,5-Dimethylphenyl)-2-isopropylindene → Lithium 4-(3,5-dimethylphenyl)-2-isopropylindenide

HRID 842504ノート

反応式

HRID 842504 の反応式
[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:17]=[CH:16][CH:15]=[C:14]3[C:10]=2[CH:11]=[C:12]([CH:18]([CH3:20])[CH3:19])[CH2:13]3)[CH:5]=[C:6]([CH3:8])[CH:7]=1.[Li:21]CCCC>CCCCC>[CH3:8][C:6]1[CH:5]=[C:4]([C:9]2[CH:17]=[CH:16][CH:15]=[C:14]3[C:10]=2[CH:11]=[C:12]([CH:18]([CH3:20])[CH3:19])[CH-:13]3)[CH:3]=[C:2]([CH3:1])[CH:7]=1.[Li+:21]

参加物

4

反応物 2

HCID 220230144-(3,5-Dimethylphenyl)-2-isopropylindeneHCID 178418339Butyllithium

生成物 1

HCID 22023013Lithium 4-(3,5-dimethylphenyl)-2-isopropylindenide

試薬・触媒・溶媒 1

HCID 8003Pentane溶媒

実験手順

4-(3′,5′-dimethylphenyl)-2-isopropylindene (5.5 g, 21 mmol) was dissolved in 80 mL of pentane. To this solution was added 8.3 mL of n-BuLi (2.5M in hexane) and the reaction was allowed to stir 4 hours at room temperature. A white solid precipitated from solution and was collected by frit filtration and washed with additional pentane. Yield was 3.3 g (60%).

後処理

  1. customA white solid precipitated from solution
  2. filtrationwas collected by frit filtration
  3. washwashed with additional pentane

出典と根拠

ORDレコード
ord-06d7454d14794cc9ae156c6c05546cf3
出典データセット
uspto-grants-2002_04
特許番号
US06376408B1

反応ノート

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