化工社化工社 化学情報印刷レポート · 研究参考用
Water → 3-Chloro-2-cyanopyrazine 1-oxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 3-Chloropyrazine-2-carbonitrile | HCID 292465 | — |
| 溶媒 | Sulfuric Acid | HCID 1118 | — |
| 生成物 | 3-Chloro-2-cyanopyrazine 1-oxide | HCID 10796992 | — |
反応手順
2-Chloro-3-cyanopyrazine (5.00 g, 35.94 mmol) in concentrated H2SO4 (35 mL) at 0° C. was treated portionwise with K2S2O8 (11.65 g, 43.95 mmol), warmed to room temperature, stirred for 24 hours, treated with water, and extracted with chloroform. The organic extract was washed sequentially with water, saturated NaHCO3 and brine, dried (MgSO4) and concentrated to provide the title compound. MS (DCI/NH3) m/e 173 (M+NH4)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06376488B1 |
| 出典データセット | uspto-grants-2002_04 |
| ORD ID | ord-aff5277d64c849fdb0f118686d72d8e9 |
| 出典メモ | uspto-grants-2002_04 |