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N-(5-chloropyridin-2-yl)-5-methyl-2-nitrobenzamide → Chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(5-chloropyridin-2-yl)-5-methyl-2-nitrobenzamide | HCID 3562519 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Platinum | HCID 23939 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Chloride | HCID 312 | — |
| 生成物 | 2-amino-N-(pyridin-2-yl)benzamide | HCID 276325 | — |
反応手順
To a solution of the compound of N-(5-chloro(2-pyridyl))(5-methyl-2-nitrophenyl)carboxamide (1.48 g, 5.11 mmol) in methanol (10 ml) was added 5% Pt/C (1.48 g, 0.19 mmol). The mixture was applied hydrogen balloon at r.t. for 2 hrs. After the filtration by Celite, the filtrate was concentrated to give (2-aminophenyl)-N-(2-pyridyl)carboxamide, C, chloride, N (1.36 g, 100%). MS found for C13H12ClN3O M+=262, (M+2)+=264.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06376515B2 |
| 出典データセット | uspto-grants-2002_04 |
| ORD ID | ord-9cb2fd961fce4261b34f0df888b013ec |
| 出典メモ | uspto-grants-2002_04 |