Benzoyl chloride → 2'-Phenylbenzohydrazide
反応式
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9](Cl)(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>CCOCC>[C:9]([NH:8][NH:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:16])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1参加物
4
反応条件
- 温度
- 5 °C
実験手順
A four neck flask (2 liters) equipped with a thermometer and a stirrer was charged with 216 g (2.0 mol) of phenylhydrazine and 1.5 liter of ether and cooled down to 5° C. Dropwise added thereto was 56.2 g (0.4 mol) of benzoyl chloride in 2 hours while stirring, and then the solution was heated to room temperature (20° C.) to continue stirring for 12 hours. Crystal was filtered off and washed sufficiently with deionized water and then dried under reduced pressure to obtain slightly brown crystal.
後処理
- customA four neck flask (2 liters) equipped with a thermometer and a stirrer
- additionDropwise added
- customin 2 hours
- temperaturethe solution was heated to room temperature (20° C.)
- stirringto continue stirring for 12 hours
- filtrationCrystal was filtered off
- washwashed sufficiently with deionized water
- customdried under reduced pressure
- customto obtain slightly brown crystal
出典と根拠
- ORDレコード
- ord-be9ef4e2ee774028b406900edcca682b
- 出典データセット
- uspto-grants-2002_04
- 特許番号
- US06380288B1
反応ノート
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