戻る
化工社化工社 化学情報印刷レポート · 研究参考用
HRID 84481作成日：2026年10月26日

3-Pyridinemethanamine → N2-(2-chlorophenyl)-N2-methyl-N8-(pyridin-3-ylmethyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2,8-dicarboxamide

https://huagongshe.com/reaction/84481

反応式

関与物質

役割名称HCID仕込み量
反応物3-PyridinemethanamineHCID 31018—
反応物2-[(2-Chloro-phenyl)-methyl-carbamoyl]-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-8-carboxylic acid methyl esterHCID 44242363—
生成物N2-(2-chlorophenyl)-N2-methyl-N8-(pyridin-3-ylmethyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2,8-dicarboxamideHCID 44242634—

反応手順

Following Example 47 and General Procedure C, methyl 2-((2-chlorophenyl)(methyl)carbamoyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-8-carboxylate 138 and 3-aminomethylpyridine gave 173. MS: (ESI+) 504.0

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08846762B2
出典データセットuspto-grants-2014_09
ORD IDord-93fe17cc42b8426fa6d31fbeb1fcc5b2
出典メモuspto-grants-2014_09