Ethanol → 2-(4-methoxyphenyl)pyrazine

反応式

[CH2:1]([NH2:4])[CH2:2][NH2:3].O.C[C:7]1[CH:12]=[CH:11][C:10]([C:13]([CH:15]=O)=O)=[CH:9][CH:8]=1.[OH-].[K+].[CH2:19]([OH:21])C>>[CH3:19][O:21][C:7]1[CH:8]=[CH:9][C:10]([C:13]2[CH:15]=[N:4][CH:1]=[CH:2][N:3]=2)=[CH:11][CH:12]=1

参加物

反応物 4

HCID 702Ethanol

HCID 3301Ethylenediamine

HCID 14797Potassium Hydroxide

HCID 212985304-Methylphenylglyoxal hydrate

生成物 1

HCID 112754552-(4-methoxyphenyl)pyrazine収率 37%

実験手順

The procedure of Example 1 was repeated, using 10.68 g (0.178 mol) of ethylenediamine, 27.0 g (0.148 mol) of 4-methylphenylglyoxal monohydrate, 200 ml of ethanol and 9.01 g of potassium hydroxide. 10.1 g of the titled compound was produced (yield: 37%).

出典と根拠

ORDレコード: ord-cccb62186aa54415b54b0bcd76789633
出典データセット: uspto-grants-1988_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04755514

反応ノート

読み込み中…