3,4-Dinitrotoluene → N,N-Dimethyl-2-(5-methyl-2-nitroanilino)ethanamine
反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH3:13])[CH:7]=[CH:8][C:9]=1[N+:10]([O-:12])=[O:11])([O-])=O.[CH3:14][N:15]([CH3:19])[CH2:16][CH2:17]N.COCCOCCN(CCOCCOC)CCOCCOC>CS(C)=O>[CH3:14][N:15]([CH3:19])[CH2:16][CH2:17][NH:1][C:4]1[CH:5]=[C:6]([CH3:13])[CH:7]=[CH:8][C:9]=1[N+:10]([O-:12])=[O:11]参加物
5
実験手順
To a stirred solution of 3,4-dinitrotoluene (3.64 g, 20 mmol) and N,N-dimethylethylenediamine (1.76 g, 20 mmol) was heated at 80° C. in dimethyl sulfoxide and catalytic amount of TDA-1 for 2 hours. N,N-Dimethyl-2-(5-methyl-2-nitroanilino)ethanamine was isolated in 80% yield (3.6 g, 16 mmol) after aqueous work-up. Quaternization was achieved in quantitative yield with methyl iodide and dimethylformamide. Its melting point was 225°-7° C.
出典と根拠
- ORDレコード
- ord-456301b9343f4a538becc55c45e476ae
- 出典データセット
- uspto-grants-1992_08
- 特許番号
- US05135543
反応ノート
読み込み中…