化工社化工社 化学情報印刷レポート · 研究参考用
Hydroxyphenylacetic acid → 2,6-Dimethylcyclohexyl 4-hydroxyphenylacetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydroxyphenylacetic acid | HCID 127 | — |
| 反応物 | Benzene | HCID 241 | — |
| 反応物 | p-Toluenesulfonic acid | HCID 6101 | — |
| 反応物 | 2,6-Dimethylcyclohexanol | HCID 21428 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2,6-Dimethylcyclohexyl 4-hydroxyphenylacetate | HCID 54109104 | 51% |
反応手順
A mixture of 2,6-dimethylcyclohexyl alcohol (11.4 g), 4-hydroxyphenylacetic acid (9.12 g), p-toluenesulfonic acid (1 g) and benzene (300 mL) was refluxed with continuous water separation for 20 hours. The mixture was filtered and the filtrate was washed with a 10% Na2CO3 solution, then with water. Drying over MgSO4 and evaporation in vacuo afforded 8.02 g of 2,6-dimethylcyclohexyl 4-hydroxyphenylacetate. That product has the structural formula: ##STR25##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05135926 |
| 出典データセット | uspto-grants-1992_08 |
| ORD ID | ord-86f9c92bf1374738bd76e2681b2a2976 |
| 出典メモ | uspto-grants-1992_08 |