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Acetonitrile → Triphenylphosphine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetonitrile | HCID 6342 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 反応物 | Triphenylphosphine | HCID 11776 | — |
| 反応物 | HCID 178514248 | HCID 178514248 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | Triphenylphosphine | HCID 11776 | — |
| 生成物 | Oxazoline | HCID 68157 | — |
反応手順
Hydroxyamide IX is then subjected to cyclodehydration in an inert organic solvent (e.g., tetrahydrofuran, acetonitrile or chloroform) under an inert atmosphere (e.g., argon) with triphenylphosphine (employing a molar ratio of V:triphenylphosphine of from about 0.8:1 to about 1:1) and carbon tetrachloride in the presence of an amine base (e.g., triethylamine or diisopropylethylamine) to form oxazoline ##STR23##
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05135939 |
| 出典データセット | uspto-grants-1992_08 |
| ORD ID | ord-9faeadff4ef440cda5bbff849c7c2f54 |
| 出典メモ | uspto-grants-1992_08 |