関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Phenol | HCID 996 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 1,2-Benzenedicarbonitrile, 4-nitro- | HCID 97443 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 4-Phenoxyphthalonitrile | HCID 371800 | — |
反応手順
A mixture is prepared by adding 104 grams (1.1 moles) of phenol, 173 grams (1 mole of 4-nitrophthalonitrile, and 207 grams of potassium carbonate in 1667 ml of dimethylformamide. The mixture is heated to 70° C. and mechanically stirred. Samples are taken of this reaction mixture periodically and analyzed by GLC. After five hours, the reaction is complete. The 4-phenoxyphthalonitrile is isolated by quenching the crude reaction mixture in ice water. The product is further purified by washing the crude precipitate with dilute sodium carbonate and then water. Finally the 4-phenoxyphthalonitrile is vacuum dried at 60° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05135972 |
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| 出典データセット | uspto-grants-1992_08 |
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| ORD ID | ord-d057e5595cc74bb0abd790e1b3340827 |
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| 出典メモ | uspto-grants-1992_08 |
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