化工社化工社 化学情報印刷レポート · 研究参考用
Carbon Tetrachloride → Diethyl chloroethylmalonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Carbon Tetrachloride | HCID 5943 | — |
| 反応物 | Diethyl ethylmalonate | HCID 8610 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 触媒 | Tetrabutylammonium chloride hydrate | HCID 16212273 | — |
| 生成物 | Diethyl chloroethylmalonate | HCID 121803 | 96% |
反応手順
Diethyl ethylmalonate (1.88 g, 10 mmol), 1.38 g (10 mmol) of potassium carbonate, 0.1 g of tetra-n-butylammonium chloride hydrate, and 5 mL of carbon tetrachloride were mixed at 70° C. for 3 h. Gas chromatographic analysis of the mixture showed complete conversion of the diethyl ethylmalonate to yield 2.13 g of diethyl α-chloro-α-ethylmalonate (96% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05138107 |
| 出典データセット | uspto-grants-1992_08 |
| ORD ID | ord-4501cb34e5af414b9100c9ace0842b7c |
| 出典メモ | uspto-grants-1992_08 |