2-Methylcarbamoyloxy-3-octadecylcarbamoyloxypropylamine → 3-(3-Chloropropylsulfonylamino)-2-methylcarbamoyloxy-1-octadecylcarbamoyloxypropane
反応式
[CH3:1][NH:2][C:3]([O:5][CH:6]([CH2:9][O:10][C:11](=[O:31])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH2:7][NH2:8])=[O:4].C(SCC(OC(=O)NC)COC(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)CCCCCCCCCCCCCCC.[Cl:77][CH2:78][CH2:79][CH2:80][S:81](NCC(OC)CSCCCCCCCCCCCCCCCC)(=[O:83])=[O:82]>>[Cl:77][CH2:78][CH2:79][CH2:80][S:81]([NH:8][CH2:7][CH:6]([O:5][C:3](=[O:4])[NH:2][CH3:1])[CH2:9][O:10][C:11](=[O:31])[NH:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])(=[O:83])=[O:82]参加物
4
反応物 3
生成物 1
実験手順
2-Methylcarbamoyloxy-3-octadecylcarbamoyloxypropylamine IV c2 is allowed to react and worked up by the same procedure as described in (4). m.p. 102°-104° C. The summary of the experimental condition and the physical data of the product are listed in the Table 7.