2-tert-Butoxycarbonylamino-3-octadecylcarbamoyloxypropylamine → 3-(3-Chloropropylsulfonylamino)-1-hexadecylthio-2-methoxymethylpropane

反応式

[C:1]([O:5][C:6](NC(COC(=O)NCCCCCCCCCCCCCCCCCC)CN)=O)(C)(C)C.[Cl:35][CH2:36][CH2:37][CH2:38][S:39]([NH:42][CH2:43][CH:44](OC)[CH2:45][S:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62])(=[O:41])=[O:40]>>[Cl:35][CH2:36][CH2:37][CH2:38][S:39]([NH:42][CH2:43][CH:44]([CH2:1][O:5][CH3:6])[CH2:45][S:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62])(=[O:40])=[O:41]

参加物

反応物 2

HCID 148350012-tert-Butoxycarbonylamino-3-octadecylcarbamoyloxypropylamine

HCID 148350223-(3-Chloropropylsulfonylamino)-1-hexadecylthio-2-methoxypropane

生成物 1

HCID 148350753-(3-Chloropropylsulfonylamino)-1-hexadecylthio-2-methoxymethylpropane

実験手順

3-Hexadecylthio-2-methoxymethylpropylamine IV k3 is allowed to react and worked up by the same procedure as described in (4). m.p. 41.5°-43° C. The summary of the experimental condition and the physical data of the product are listed in Table 7.

後処理

customto react

出典と根拠

ORDレコード: ord-285e7716512b475abe34f9b38eecdf93
出典データセット: uspto-grants-1992_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05138067

反応ノート

読み込み中…