1,2-Dichloroethane → HCID 19882549、化合物
反応式
[OH:1][C:2]1[C:11]([OH:12])=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][C:7]2=[O:13].Cl[CH2:15][CH2:16]Cl.C([O-])([O-])=O.[K+].[K+]>CS(C)=O>[CH2:15]1[CH2:16][O:12][C:11]2[C:2](=[C:3]3[C:8](=[CH:9][CH:10]=2)[C:7](=[O:13])[CH2:6][CH2:5][CH2:4]3)[O:1]1参加物
5
実験手順
5,6-Dihydroxy-1-tetralone (6 g) was heated at 125° C. with 1,2-dichloroethane (7 ml) and K2CO3 (14 g) in DMSO (70 ml) under N2 for 45 min. The reaction was quenched with ice water then extracted with Et2O. The aqueous layer was removed, then EtOAc added to the remaining organics. This solution was dried (MgSO4), filtered and evaporated to give the desired product.
後処理
- customThe reaction was quenched with ice water
- extractionthen extracted with Et2O
- customThe aqueous layer was removed
- additionEtOAc added to the remaining organics
- dry with materialThis solution was dried (MgSO4)
- filtrationfiltered
- customevaporated
出典と根拠
- ORDレコード
- ord-4828b4d186554648ac9f5712d539e94e
- 出典データセット
- uspto-grants-1992_08
- 特許番号
- US05140040
反応ノート
読み込み中…