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2-Chlorobenzamide → 1-(2-Chlorobenzoyl)-3-(5-trifluoromethyl-2-pyrazinyl)urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Chlorobenzamide | HCID 69111 | — |
| 反応物 | 2-Isocyanatopyrazine | HCID 18987644 | — |
| 反応物 | Pyrazine, 2-isocyanato-5-(trifluoromethyl)- | HCID 20567021 | — |
| 生成物 | 1-(2-Chlorobenzoyl)-3-(5-trifluoromethyl-2-pyrazinyl)urea | HCID 13341081 | — |
反応手順
A compound of formula I may also be prepared by allowing a 2-substituted benzamide to react with a 2-pyrazinylisocyanate utilizing the appropriate solvents, times of reaction and general reaction conditions hereinabove described. For example, 2-chlorobenzamide is allowed to react with 5-trifluoromethylpyrazin-2-ylisocyanate to yield 1-(2-chlorobenzoyl)-3-(5-trifluoromethyl-2-pyrazinyl)urea, having a melting point of about 219°-220° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04293552 |
| 出典データセット | uspto-grants-1981_10 |
| ORD ID | ord-201e548ca6654fdda4946ea34b17dce2 |
| 出典メモ | uspto-grants-1981_10 |