Hydrochloric Acid → 1-Propanone, 3-(1H-imidazol-1-yl)-1-(2-naphthalenyl)-, monohydrochloride
反応式
[ClH:1].[CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[C:12]([CH2:14][CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)=[O:13]>C1C=CC=CC=1>[ClH:1].[CH:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][C:3]=1[C:12]([CH2:14][CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)=[O:13]参加物
4
実験手順
Ethereal hydrogen chloride is added dropwise to a solution of 1.0 g 1-[2-(2-naphthoyl)ethyl]imidazole in 100 ml anhydrous benzene until precipitation is complete. The product is filtered, washed with ether, air dried and recrystallized from methanol/acetone to yield 1-[2-(2-naphthoyl)ethyl]imidazole hydrochloride, m.p. 182.5°-186° C.
後処理
- filtrationThe product is filtered
- washwashed with ether, air
- customdried
- customrecrystallized from methanol/acetone
出典と根拠
- ORDレコード
- ord-8c4a0d0dbddd4b87ad44a50ae0c0a067
- 出典データセット
- uspto-grants-1981_10
- 特許番号
- US04293561
反応ノート
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