化工社化工社 化学情報印刷レポート · 研究参考用
3-Ethoxy-2-methyl-6-nitropyridine → 5-Ethoxy-6-methylpyridin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Ethoxy-2-methyl-6-nitropyridine | HCID 12875016 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 5-Ethoxy-6-methylpyridin-2-amine | HCID 12875017 | 90.8% |
反応手順
18.2 g of the nitro compound obtained above was suspended in 300 ml of ethanol, which was reduced over 2 g of 5% palladium black under atmospheric pressure. After reaction, the catalyst was filtered off and the solvent was evaporated in vacuo. The residue was crystallized from benzene to obtain 13.8 g of 3-ethoxy-2-methyl-6-aminopyridine (Compound IV where R2 =C2H5), m.p. 98°-99° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04293695 |
| 出典データセット | uspto-grants-1981_10 |
| ORD ID | ord-7546caff650d435fac3441641d4fbc59 |
| 出典メモ | uspto-grants-1981_10 |