Methanol → HCID 20566262、化合物

HRID 848065ノート

反応式

HRID 848065 の反応式
C1(C)C=C(C)C=C(C)C=1S(O)(=O)=[O:10].[C:14]1([S:20]([C:22]2[S:23][CH:24]=[CH:25][CH:26]=2)=[NH:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CO.I([O-])(=O)(=O)=O.[Na+]>O>[C:14]1([S:20]([C:22]2[S:23][CH:24]=[CH:25][CH:26]=2)(=[NH:21])=[O:10])[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

参加物

5

反応物 3

HCID 887MethanolHCID 23667635Sodium periodateHCID 88772777HCID 88772777、化合物

生成物 1

HCID 20566262HCID 20566262、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

10 g. Phenyl-(2-thienyl)-sulphimide mesitylene-sulphonate are dissolved in 200 ml. methanol. A solution of 7 g. sodium periodate in 150 ml. water are added dropwise thereto, whereafter the reaction mixture is stirred for 24 hours at ambient temperature. The reaction mixture is then rendered alkaline and evaporated on a rotary evaporator. The residue obtained is partitioned between water and dichloromethane and the organic phase is evaporated. There are obtained 3.7 g. phenyl-(2-thienyl)-sulphoximide which, after recrystallisation from ethyl acetate/isopropanol, melts at 133° C.

後処理

  1. customevaporated on a rotary evaporator
  2. customThe residue obtained
  3. customis partitioned between water and dichloromethane
  4. customthe organic phase is evaporated
  5. customThere are obtained 3.7 g
  6. customphenyl-(2-thienyl)-sulphoximide which, after recrystallisation from ethyl acetate/isopropanol, melts at 133° C.

出典と根拠

ORDレコード
ord-f81957d4d822446ea1b6ad6d4afd2384
出典データセット
uspto-grants-1981_10
特許番号
US04294838

反応ノート

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