Ammonium Acetate → 3-Amino-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one
反応式
C([O-])(=O)C.[NH4+:5].[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([N:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:16]=[C:15](OCC)[C:14]2=[O:26])=[CH:9][CH:8]=1>O>[NH2:5][C:15]1[C:14](=[O:26])[N:13]([C:10]2[CH:11]=[CH:12][C:7]([Cl:6])=[CH:8][CH:9]=2)[C:22]2[C:17]([N:16]=1)=[CH:18][CH:19]=[CH:20][CH:21]=2参加物
4
実験手順
To a melt of ammonium acetate (62 g) at 160° C. was added 1-(4-chlorophenyl)-1,2-dihydro-3-ethoxyquinoxalin-2-one (8.8 g) and the temperature was then raised during 5 minutes to 200° C. and maintained at this level for 15 minutes. The melt was cooled, water was added, and the product was filtered off. Crystallisation from ethanol gave the title compound (5.6 g) mp 254°-255° C.
後処理
- temperaturethe temperature was then raised during 5 minutes to 200° C.
- temperaturemaintained at this level for 15 minutes
- temperatureThe melt was cooled
- filtrationthe product was filtered off
- customCrystallisation from ethanol
出典と根拠
- ORDレコード
- ord-6a044e9c5d98424e8147b462d0d79187
- 出典データセット
- uspto-grants-1981_10
- 特許番号
- US04296114
反応ノート
読み込み中…