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Methanesulfonic Acid → 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanesulfonic Acid | HCID 6395 | — |
| 反応物 | 2-Hydroxy-5-(hydroxymethyl)benzaldehyde | HCID 53142 | — |
| 反応物 | Thiobarbituric acid | HCID 2723628 | — |
| 溶媒 | 1-Butanol | HCID 263 | — |
| 生成物 | 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione | HCID 20564257 | — |
反応手順
To a solution of 5-hydroxymethyl-salicylaldehyde (5.8 g.) and 2-thiobarbituric acid (6 g.) in n-butanol (100 ml.) add methanesulfonic acid (10 ml.) and heat to reflux, with stirring, for 1 hour. Cool, filter and wash the solid with ethanol and ether to yield 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04297355 |
| 出典データセット | uspto-grants-1981_10 |
| ORD ID | ord-e2191dd56f2446eeb0103dd94f1827d4 |
| 出典メモ | uspto-grants-1981_10 |