Potassium Carbonate → HCID 18800645、化合物

HRID 849085

反応式

HRID 849085 の反応式
[C:1]([CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11])([O:3][CH3:4])=[O:2].Br[CH2:13][CH2:14][CH:15]1[O:19][CH2:18][CH2:17][O:16]1.C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C.O>[O:16]1[CH2:17][CH2:18][O:19][CH:15]1[CH2:14][CH2:13][C:5]1([C:1]([O:3][CH3:4])=[O:2])[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11]

参加物

6

反応物 3

HCID 11430Potassium CarbonateHCID 877762-(2-Bromoethyl)-1,3-dioxolaneHCID 170489Cyclohexanecarboxylic acid, 2-oxo-, methyl ester

生成物 1

HCID 18800645HCID 18800645、化合物

試薬・触媒・溶媒 2

HCID 962Water溶媒HCID 6228Dimethylformamide溶媒

実験手順

A solution of 2-carbomethoxycyclohexanone (2.0 g, 12.8 mmoles) in 50 mL of DMF was reacted at 70° C. for 15 h with 2-(2-bromoethyl)-1,3-dioxolane (4.6 g, 25 moles) and potassium carbonate (4.8 g, 34.8 mmoles). The reaction mixture was diluted to 500 mL with water and extracted with ethyl ether/ethyl acetate. The organic extracts were dried over sodium sulfate, and the solvent was evaporated to generate the title compound as an oil.

後処理

  1. extractionextracted with ethyl ether/ethyl acetate
  2. dry with materialThe organic extracts were dried over sodium sulfate
  3. customthe solvent was evaporated

出典と根拠

ORDレコード
ord-fee485bb624b42ff99cd221a42969cd4
出典データセット
uspto-grants-2000_01
特許番号
US06011028

関連ノート

読み込み中…