化工社化工社 化学情報印刷レポート · 研究参考用
6-Benzylpyridin-2-amine → 2-Imino-6-cyclohexylmethylpiperidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Benzylpyridin-2-amine | HCID 93902 | — |
| 触媒 | Platinum oxide (PtO) | HCID 82844 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-Imino-6-cyclohexylmethylpiperidine | HCID 178507545 | — |
反応手順
The 2-amino-6-benzylpyridine product of Example 298 A was reduced in acetic acid under hydrogen atmosphere utilizing platinum oxide catalyst to afford 2-imino-6-cyclohexylmethylpiperidine as an oil. The oil was dissolved in 1N HCl and lyophilized to give a white solid. The solid was recrystallized from EtOAc to give the title product as white crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06011028 |
| 出典データセット | uspto-grants-2000_01 |
| ORD ID | ord-c54b6b59a77b4a6d895f822e4a0e7eee |
| 出典メモ | uspto-grants-2000_01 |