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Hydrochloric Acid → 1-Aminocyclopentane-1-carboxamide hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 1-Tert-butoxycarbonylamino-1-cyclopentanecarboxamide | HCID 10680867 | — |
| 溶媒 | 1,4-Dioxane | HCID 31275 | — |
| 生成物 | 1-Aminocyclopentane-1-carboxamide hydrochloride | HCID 54593188 | — |
反応手順
A solution of tert-butyl 1-carbamoylcyclopentylcarbamate (305 mg, 1.33 mmol) in 4N HCl in dioxane (5 mL) and aq. 6N HCl (3 mL) was stirred at room temperature for 3 h. It was then concentrated in vacuo to give 1-aminocyclopentanecarboxamide hydrochloride as a solid (214 mg).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08846928B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-a43fbb7c1ba4499c8a9ed229a92ef8a5 |
| 出典メモ | uspto-grants-2014_09 |