関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Piperazine | HCID 4837 | — |
| 反応物 | 4-Fluorobenzenesulfonamide | HCID 120231 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-(Piperazin-1-yl)benzene-1-sulfonamide | HCID 901897 | 96.1% |
反応手順
A mixture of 4-fluorobenzenesulfonamide (6.95 g) and piperazine (17.1 g) in 30 mL of water is heated at 100° C. overnight. The solid is then collected, washed with water and toluene, and dried under reduced pressure to give 9.2 g of 4-(piperazin-1-yl)benzenesulfonamide; mp 219-221° C.; ms m/z 241; IR (mineral oil) 1160, 822, 1332, 608, 1593, 1137 cm-1. 1H NMR (DMSOd6) δ 2.81, 3.17, 2.3, 7.01, 7.07, 7.61.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06013654 |
|---|
| 出典データセット | uspto-grants-2000_01 |
|---|
| ORD ID | ord-04797938215e4ceb83bc79bdad90df9d |
|---|
| 出典メモ | uspto-grants-2000_01 |
|---|
