Hydrochloric Acid → 2-Phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

HRID 850030ノート

反応式

HRID 850030 の反応式
C([N:8]1[CH2:13][CH2:12][C:11]2[S:14][C:15]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:16][C:10]=2[CH2:9]1)(OC(C)(C)C)=O.[ClH:23]>CCOC(C)=O>[ClH:23].[C:17]1([C:15]2[S:14][C:11]3[CH2:12][CH2:13][NH:8][CH2:9][C:10]=3[CH:16]=2)[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 19365863N-Boc-2-phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

生成物 1

HCID 193658652-Phenyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

反応条件

温度
0 °C

実験手順

The product from Step 2 was dissolved in EtOAc at -25° C. and treated with HCl gas until saturated. The reaction was stoppered and stirred at 0° C. for 1 h. Removal of the solvent in vacuo afforded the title compound as a solid.

後処理

  1. customRemoval of the solvent in vacuo

出典と根拠

ORDレコード
ord-63709392ff064df389811790be09d5cd
出典データセット
uspto-grants-2000_01
特許番号
US06015817

反応ノート

読み込み中…