alpha-Bromo-o-fluorotoluene → 2-(2-Fluorophenyl)-4'-iodoacetophenone

反応式

[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4]Br.CON(C)[C:13]([C:15]1[CH:20]=[CH:19][C:18]([I:21])=[CH:17][CH:16]=1)=[O:14]>>[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][C:13]([C:15]1[CH:20]=[CH:19][C:18]([I:21])=[CH:17][CH:16]=1)=[O:14]

参加物

反応物 2

HCID 67968alpha-Bromo-o-fluorotoluene

HCID 54617564-Iodo-N-methoxy-N-methyl-benzamide

生成物 1

HCID 193659392-(2-Fluorophenyl)-4'-iodoacetophenone

実験手順

The product was prepared from 2-fluorobenzyl bromide and O,N-dimethyl-4-iodobenzenehydroxamic acid (see Preparation 30) by a similar method to Preparation 20(i) as a colourless solid, m.p. 112-114° C.

出典と根拠

ORDレコード: ord-20e099695ebc4c4d92f9fbd0a7999eca
出典データセット: uspto-grants-2000_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06015825

反応ノート

読み込み中…