Potassium Hydroxide → Ethyl (3,5-di-t-butyl-4-oxocyclohexa-2,5-dienylidene)acetate

HRID 850334ノート

反応式

HRID 850334 の反応式
[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].[OH-].[K+]>C1C=CC=CC=1.O.[Fe-3](C#N)(C#N)(C#N)(C#N)(C#N)C#N.[K+].[K+].[K+]>[C:12]([C:9]1[C:10](=[O:11])[C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])=[CH:6][C:7](=[CH:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:8]=1)([CH3:13])([CH3:14])[CH3:15]

参加物

6

反応物 2

HCID 14797Potassium HydroxideHCID 13908126Ethyl (3,5-di-t-butyl-4-hydroxyphenyl)-acetate

生成物 1

HCID 22019852Ethyl (3,5-di-t-butyl-4-oxocyclohexa-2,5-dienylidene)acetate

試薬・触媒・溶媒 3

HCID 178511488HCID 178511488、化合物触媒HCID 241Benzene溶媒HCID 962Water溶媒

反応条件

温度
40 °C

実験手順

In benzene (150 mL) was dissolved Intermediate 10 (6.7 g, 22.9 mmol) and this treated with a solution of potassium hydroxide (13.9 g [85%], 210 mmol) and potasium ferricyanide (K3Fe(CN)6) (15.2 g, 46 mmol) in water (150 mL). The mixture stirred under nitrogen atmosphere at 40° C. for 2 hours. The benzene layer then separated, washed with brine (100 mL) and dried over magnesium sulfate. The solvent was evaporated in vacuo to give a red oil, 6.1 g (92%), which was used as is.

後処理

  1. customThe benzene layer then separated
  2. washwashed with brine (100 mL)
  3. dry with materialdried over magnesium sulfate
  4. customThe solvent was evaporated in vacuo
  5. customto give a red oil, 6.1 g (92%), which

出典と根拠

ORDレコード
ord-4eae0ab84fa34408a0f311abf2920d41
出典データセット
uspto-grants-2000_01
特許番号
US06017918

反応ノート

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