Methyl Isocyanate → N-methyl-carbamic acid O-(1-iso-propylpyrazol-4-yl) ester
反応式
[CH3:1][N:2]=[C:3]=[O:4].[CH:5]([N:8]1[CH:12]=[C:11]([OH:13])[CH:10]=[N:9]1)([CH3:7])[CH3:6]>CC(C)=O.C(N(CC)CC)C>[CH:5]([N:8]1[CH:12]=[C:11]([O:13][C:3](=[O:4])[NH:2][CH3:1])[CH:10]=[N:9]1)([CH3:7])[CH3:6]参加物
5
反応条件
- 温度
- 45 °C
実験手順
6 g (0.105 mol) of methyl isocyanate were added to a solution of 12.6 g (0.1 mol) of 1-isopropyl-4-hydroxy-pyrazole in 100 ml of acetone and 2 drops of triethylamine. The mixture was stirred at 45° C. for 12 hours and the solvent was then distilled off in vacuo. 17.4 g (95% of theory) of N-methyl-carbamic acid O-(1-iso-propylpyrazol-4-yl) ester were thus obtained in the form of beige crystals with a melting point of 40° C.
後処理
- distillationthe solvent was then distilled off in vacuo
出典と根拠
- ORDレコード
- ord-d3a9672dd9d346b18070dfedfc708c8a
- 出典データセット
- uspto-grants-1983_05
- 特許番号
- US04382947
反応ノート
読み込み中…