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3,4,5-Trimethoxyphenol → 1,2,3,4-Tetrahydro-8,9,10-trimethoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,4,5-Trimethoxyphenol | HCID 69505 | — |
| 反応物 | Methyl 4-oxopiperidine-3-carboxylate hydrochloride | HCID 2724028 | — |
| 生成物 | 1,2,3,4-Tetrahydro-8,9,10-trimethoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one hydrochloride | HCID 13136914 | 55% |
反応手順
Prepared by the method described in Example 1 from 3,4,5-trimethoxyphenol (25 g, 0.14 moles) and methyl 4-oxo-3-piperidinecarboxylate hydrochloride (18.8 g, 0.097 moles). Recrystallization from dilute aqueous hydrochloric acid yielded the product (17.5 g) as the hydrochloride, mp 232°-234° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04382939 |
| 出典データセット | uspto-grants-1983_05 |
| ORD ID | ord-32bc5c3456fd4bc0b985babfe6c8a89f |
| 出典メモ | uspto-grants-1983_05 |