Diethylamine → Ethyl 3-(diethylamino)acrylate

HRID 851528

反応式

HRID 851528 の反応式
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].[C:6]([O:10][CH2:11][CH3:12])(=[O:9])[C:7]#[CH:8]>C(O)C>[CH2:1]([N:3]([CH2:4][CH3:5])[CH:8]=[CH:7][C:6]([O:10][CH2:11][CH3:12])=[O:9])[CH3:2]

参加物

4

反応物 2

HCID 8021DiethylamineHCID 12182Ethyl propiolate

生成物 1

HCID 139639Ethyl 3-(diethylamino)acrylate収率 87.3%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

A solution of 14.6 g of diethylamine (0.2 m) in 100 ml of ethyl alcohol was added dropwise to a stirred solution of 19.6 g of ethyl propiolate (0.2 m) in 150 ml ethyl alcohol at room temperature. The exothermic reaction mixture was stirred at room temperature for 31/2 hours. The solvent was removed and the residue distilled through a short Vigreux column (boiling point 88° C./6 mm) to give 29.83 g (87 percent) of ethyl 3-(diethylamino)acrylate.

後処理

  1. customThe solvent was removed
  2. distillationthe residue distilled through a short Vigreux column (boiling point 88° C./6 mm)

出典と根拠

ORDレコード
ord-0b06bf0c933740fba8f5b4cf630880fd
出典データセット
uspto-grants-1983_05
特許番号
US04385104

関連ノート

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