Toluene → HCID 54150769、化合物

HRID 851814ノート

反応式

HRID 851814 の反応式
C1(S([CH2:10][CH2:11][CH2:12][CH:13]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][C:14]2=O)(=O)=O)C=CC=CC=1.CCC([O-])(C)C.[Na+].C1(C)C=CC=CC=1>CS(C)=O>[C:13]12[CH2:12][CH2:11][CH:10]=[C:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH:24]=2

参加物

5

反応物 3

HCID 1140TolueneHCID 2733478Sodium 2-methylbutan-2-olateHCID 205012032-[3-(Benzenesulfonyl)propyl]cyclododecan-1-one

生成物 1

HCID 54150769HCID 54150769、化合物収率 76%

試薬・触媒・溶媒 1

HCID 679Dimethyl Sulfoxide溶媒

実験手順

18.2 g (0.05 mole) of 2-(3-phenylsulfonyl-prop-1-yl)-cyclododecanone, 33.0 g (0.30 mole) of sodium tert-pentoxide and 100 ml of toluene were subjected to the treatments described sub letter (a). After addition of 15 ml of DMSO, heating at 110° for 4 hours and final treatments as indicated hereinabove, there were isolated 7.75 g (76% yield) of the desired compound.

後処理

  1. temperatureheating at 110° for 4 hours

出典と根拠

ORDレコード
ord-b0c9d227e12b48c1a1612dd3c3da023d
出典データセット
uspto-grants-1983_05
特許番号
US04386220

反応ノート

読み込み中…