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Cyclohexanol → HCID 58612895、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cyclohexanol | HCID 7966 | — |
| 反応物 | 1,2,3-Propanetricarboxylic acid | HCID 14925 | — |
| 触媒 | p-Toluenesulfonic acid | HCID 6101 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 溶媒 | Heptane | HCID 8900 | — |
| 生成物 | HCID 58612895 | HCID 58612895 | 83.4% |
反応手順
A mixture of 1,2,3-propanetricarboxylic acid (25 g), cyclohexanol (55 g), and p-toluenesulfonic acid (100 mg) in toluene (500 mL) was refluxed for 2 days and water removed from the reaction mixture. After reaction was complete, solvent was removed in vacuuo to yield a viscous oil. The crude material was redissolved in heptane and passed through a pad of silica gel to obtain 1,2,3-propanetricarboxylic acid tricyclohexyl ester (50 g) as a pale yellow oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07252865B2 |
| 出典データセット | uspto-grants-2007_08 |
| ORD ID | ord-7e233837b41f4ef9a3784255f4e715dd |
| 出典メモ | uspto-grants-2007_08 |