2-Ethylbenzimidazole → 2-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole

HRID 851845

反応式

HRID 851845 の反応式
[CH2:1]([C:3]1[NH:4][C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:2].[CH3:12][O:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18]Cl>>[CH2:1]([C:3]1[N:4]([CH2:18][CH2:17][O:16][CH2:15][CH2:14][O:13][CH3:12])[C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:2]

参加物

3

反応物 2

HCID 158072-EthylbenzimidazoleHCID 94934Ethane, 1-(2-chloroethoxy)-2-methoxy-

生成物 1

HCID 44742762-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole収率 77%

実験手順

2-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-ethylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-methoxyethyl ether was used instead of 2-chloroethyl methyl ether. Yield 77%.

出典と根拠

ORDレコード
ord-6f8ac4ad6ece44e596a4f65f55eb6963
出典データセット
uspto-grants-2007_08
特許番号
US07252925B2

関連ノート

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