Dimethylformamide dimethyl acetal → HCID 72466433、化合物
反応式
[C:1]([C:3]1[CH:4]=[C:5]([NH:9][C:10]([NH2:12])=[S:11])[CH:6]=[CH:7][CH:8]=1)#[N:2].CO[CH:15](OC)[N:16]([CH3:18])[CH3:17]>>[CH3:15][N:16]([CH:18]=[N:12][C:10]([NH:9][C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([C:1]#[N:2])[CH:4]=1)=[S:11])[CH3:17]参加物
3
反応条件
- 温度
- 100 °C
実験手順
A mixture of 3 g (16.9 mmol) 1-(3-Cyanophenyl)-2-thiourea and 20 ml N,N-Dimethylformamide dimethyl acetal was heated to 100° C. for 1 h. After evaporation of the volatiles the precipitate was suspended in DCM, filtered and dried to yield 3.56 g (91%) of the title compound.
後処理
- customAfter evaporation of the volatiles the precipitate
- filtrationfiltered
- customdried
出典と根拠
- ORDレコード
- ord-8095ad6076e34d819f9678fc783a9013
- 出典データセット
- uspto-grants-2007_08
- 特許番号
- US07253197B2
反応ノート
読み込み中…