Dimethylformamide dimethyl acetal → HCID 72466434、化合物

HRID 852439ノート

反応式

HRID 852439 の反応式
[NH:1]([C:5]1[CH:6]=[C:7]([S:11]([NH2:14])(=[O:13])=[O:12])[CH:8]=[CH:9][CH:10]=1)[C:2]([NH2:4])=[S:3].CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>>[CH3:17][N:18]([CH:20]=[N:14][S:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([NH:1][C:2]([N:4]=[CH:17][N:18]([CH3:20])[CH3:19])=[S:3])[CH:6]=1)(=[O:12])=[O:13])[CH3:19]

参加物

3

反応物 2

HCID 78373Dimethylformamide dimethyl acetalHCID 431489173-Thioureido-benzenesulfonamide

生成物 1

HCID 72466434HCID 72466434、化合物収率 82%

実験手順

A mixture of 2.3 g (9.9 mmol) 3-Thioureido-benzenesulfonamide and 17 ml N,N-Dimethylformamide dimethyl acetal was heated for 2 h to 90° C. The precipitate was filtered of washed with DCM/diethyl ether 1:3 and dried to yield 2.8 g (82%) of the title compound.

後処理

  1. temperaturewas heated for 2 h to 90° C
  2. filtrationThe precipitate was filtered
  3. washof washed with DCM/diethyl ether 1:3
  4. customdried

出典と根拠

ORDレコード
ord-4452ed59d260418a942b5ff2ee2dd0e4
出典データセット
uspto-grants-2007_08
特許番号
US07253197B2

反応ノート

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