Isobutyl mercaptan → 1,1-Dimethylethyl {1,1-dimethyl-2-[(2-methylpropyl)thio]ethyl)carbamate

反応式

CS(O[CH2:6][C:7]([NH:10][C:11]([O:13][C:14]([CH3:17])([CH3:16])[CH3:15])=[O:12])([CH3:9])[CH3:8])(=O)=O.CC(NC(=O)OC(C)(C)C)(C)COC1C=CC=CC=1.[CH3:37][CH:38]([CH3:41])[CH2:39][SH:40]>>[CH3:8][C:7]([NH:10][C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])([CH3:9])[CH2:6][S:40][CH2:39][CH:38]([CH3:41])[CH3:37]

参加物

反応物 3

HCID 10558Isobutyl mercaptan

HCID 11659022Methanesulfonic acid 2-tert-butoxycarbonylamino-2-methyl-propyl ester

HCID 866028801,1-Dimethylethyl [1,1-dimethyl-2-(phenyloxy)ethyl]carbamate

生成物 1

HCID 866028811,1-Dimethylethyl {1,1-dimethyl-2-[(2-methylpropyl)thio]ethyl)carbamate

実験手順

1,1-Dimethylethyl {1,1-dimethyl-2-[(2-methylpropyl)thio]ethyl}carbamate (D276) was prepared from 2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-2-methylpropyl methanesulfonate (D273) in an analogous manner to 1,1-dimethylethyl [1,1-dimethyl-2-(phenyloxy)ethyl]carbamate (D274) using 2-methyl-1-propanethiol instead of phenol.

出典と根拠

ORDレコード: ord-053338bbbe3c498ebde2bb7254dcc943
出典データセット: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07253198B2

反応ノート

読み込み中…

参加物