4-[2-[4-(Dibutylamino)phenyl]vinyl]benzyl alcohol → 4-{2-[4-(Dibutylamino)phenyl]ethenyl}benzaldehyde

HRID 85344ノート

反応式

HRID 85344 の反応式
[CH2:1]([N:5]([CH2:22][CH2:23][CH2:24][CH3:25])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][C:14]2[CH:21]=[CH:20][C:17]([CH2:18][OH:19])=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]>ClCCl.[O-2].[O-2].[Mn+4]>[CH2:22]([N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][C:14]2[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:23][CH2:24][CH3:25]

参加物

4

反応物 1

HCID 680087414-[2-[4-(Dibutylamino)phenyl]vinyl]benzyl alcohol

生成物 1

HCID 713628364-{2-[4-(Dibutylamino)phenyl]ethenyl}benzaldehyde収率 64.1%

試薬・触媒・溶媒 2

HCID 178418406HCID 178418406、化合物触媒HCID 6344Dichloromethane溶媒2 回

実験手順

In 30 ml of dichloromethane was suspended 6.0 g (69.0 mmol) of active manganese dioxide. Next, 1.17 g (3.45 mmol) of 4-[2-[4-(dibutylamino)phenyl]vinyl]benzyl alcohol was dissolved in dichloromethane and added to the suspension. After stirred at room temperature for 20 hours, the suspension was filtrated and the solvent was evaporated off. The residue was purified by silica gel column, chromatography to give 0.74 g of a yellow crystal (yield: 64.1%).

後処理

  1. additionadded to the suspension
  2. filtrationthe suspension was filtrated
  3. customthe solvent was evaporated off
  4. customThe residue was purified by silica gel column, chromatography

出典と根拠

ORDレコード
ord-7a2dbfd4835043ee919503c0d17b2a8b
出典データセット
uspto-grants-2014_09
特許番号
US08846955B2

反応ノート

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