1-(2,5-Bis(2,2,2-trifluoroethoxy)phenyl)ethan-1-one → 1-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-3-[2,4-bis-(trifluoromethyl)phenyl]prop-2-en-1-one

関与物質

反応手順

The title compound was prepared from a mixture of 2,5-bis(2,2,2-trifluoroethoxy)acetophenone (200 mg, 0.633 mmol) and 2,4-bis(trifluoromethyl)benzaldehyde (108 ul, 0.633 mmol) similar to Example 6 as a yellow solid (27 mg, 8%). 1H NMR (CDCl3): 8.03 (dd, J=2.0, 15.5 Hz, 1H), 7.97 (s, 1H), 7.93 (d, J=8.1 Hz, 1H), 7.86 (d, J=7.2 Hz, 1H), 7.50 (d, J=15.6 Hz, 1H), 7.35 (d, J=3.3 Hz, 1H), 7.18 (dd, J=3.3, 9.0 Hz, 1H), 6.95 (d, J=9.3 Hz, 1H), 4.47-4.35 (m, 4H).

情報源と証拠