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HRID 85395作成日：2026年10月26日

Diflunisal → 2',4'-Difluoro-4-hydroxy-N-(2-(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11, 14,17-pentaenamidoethyl)biphenyl-3-carboxamide

https://huagongshe.com/reaction/85395

反応式

関与物質

役割名称HCID仕込み量
反応物DiflunisalHCID 3059—
反応物EdasalonexentHCID 44626120—
生成物2',4'-Difluoro-4-hydroxy-N-(2-(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11, 14,17-pentaenamidoethyl)biphenyl-3-carboxamideHCID 59193203—

反応手順

2′,4′-Difluoro-4-hydroxy-N-(2-(5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenamidoethyl)biphenyl-3-carboxamide was prepared in a similar fashion as N-(2-(4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenamidoethyl)-2-hydroxybenzamide, using the appropriate 2′,4′-difluoro-4-hydroxybiphenyl-3-carboxylic acid and EPA starting materials. Mass calculated for C35H42F2N2O3=576.72; found: [M+H]+=577.3.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08846972B2
出典データセットuspto-grants-2014_09
ORD IDord-7fddb48775ae4c50ac82914ecd6e76ad
出典メモuspto-grants-2014_09