3-(2-Hydroxyethyl)hydrazono-2-hydroxyiminopropionitrile → 1H-Pyrazole-1-ethanol, 5-amino-4-nitroso-

In a flask having an inner volume of 25 ml and equipped with a stirring device, a thermometer and a reflux condenser were charged 0.94 g (6 mmol) of 3-(2-hydroxyethyl)hydrazono-2-hydroxyiminopropionitrile synthesized by the same method as in Example 5 and 6 ml of n-butyl alcohol, and the mixture was reacted at 110° C. for 3 hours, and further at 5 to 10° C. for 1 hour. After completion of the reaction, the reaction mixture was filtered, and the filtrate was dried under reduced pressure to give 0.61 g (isolation yield: 64%) of 5-amino-1-(2-hydroxyethyl)-4-nitrosopyrazole as reddish orange crystal.

1. customIn a flask having
2. customan inner volume of 25 ml and equipped with a stirring device
3. customthe mixture was reacted at 110° C. for 3 hours
4. customAfter completion of the reaction
5. filtrationthe reaction mixture was filtered
6. customthe filtrate was dried under reduced pressure

ORDレコード

ord-d98a8146174f46c5bc979274264d70b0

出典データセット

uspto-grants-2007_08

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US07256304B2