Cuminaldehyde → 4-Iodomethyl-2-(4-isopropylphenyl)-5-methyloxazole

反応式

[I:1][CH2:2][C:3]1[N:4]=C(C2C=CC(C)=CC=2)O[C:7]=1[C:8]1C=CC=CC=1.C/C(/C(C)=O)=N\O.[CH:28]([C:31]1[CH:38]=[CH:37][C:34]([CH:35]=[O:36])=[CH:33][CH:32]=1)([CH3:30])[CH3:29]>>[I:1][CH2:2][C:3]1[N:4]=[C:35]([C:34]2[CH:33]=[CH:32][C:31]([CH:28]([CH3:30])[CH3:29])=[CH:38][CH:37]=2)[O:36][C:7]=1[CH3:8]

参加物

反応物 3

HCID 326Cuminaldehyde

HCID 64096332,3-Butanedione monoxime

HCID 574345044-Iodomethyl-5-phenyl-2-p-tolyloxazole

生成物 1

HCID 574345184-Iodomethyl-2-(4-isopropylphenyl)-5-methyloxazole

実験手順

Analogously to the building block synthesis of 4-iodomethyl-5-phenyl-2-p-tolyloxazole, diacetylmonoxime and 4-isopropylbenzaldehyde gave 4-iodomethyl-2-(4-isopropylphenyl)-5-methyloxazole.

出典と根拠

ORDレコード: ord-33272bf5d43046cdb6900fc72b650a1f
出典データセット: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07259177B2

反応ノート

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