Phenylhydrazine → 9-Ethyl-3-carbazolecarbaldehyde phenylhydrazone

HRID 8557

反応式

HRID 8557 の反応式
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:9]([N:11]1[C:23]2[CH:22]=[CH:21][C:20]([CH:24]=O)=[CH:19][C:18]=2[C:17]2[C:12]1=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH3:10]>C(O)(C)C>[C:1]1([NH:7][N:8]=[CH:24][C:20]2[CH:21]=[CH:22][C:23]3[N:11]([CH2:9][CH3:10])[C:12]4[C:17]([C:18]=3[CH:19]=2)=[CH:16][CH:15]=[CH:14][CH:13]=4)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 7516PhenylhydrazineHCID 820559-ethyl-9H-carbazole-3-carbaldehyde

生成物 1

HCID 688623579-Ethyl-3-carbazolecarbaldehyde phenylhydrazone

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

Phenylhydrazine (0.1 mole, commercially available from Aldrich, Milwaukee, Wis.) and 9-ethyl-3-carbazolecarboxaldehyde (0.1 mole, available from Aldrich Chemical, Milwaukee, Wis.) were dissolved in 100 ml of isopropanol in 250 ml 3-neck round bottom flask equipped with a reflux condenser and a mechanical stirrer. The solution was refluxed for 2 hours. Thin layer chromatography indicated the disappearance of the starting materials. At the end of the reaction, the mixture was cooled to room temperature. The 9-ethyl-3-carbazolecarbaldehyde phenylhydrazone crystals formed upon standing were filtered off and washed with isopropanol and dried in a vacuum oven at 50° C. for 6 hours.

後処理

  1. customequipped with a reflux condenser and a mechanical stirrer
  2. temperatureThe solution was refluxed for 2 hours
  3. customAt the end of the reaction

出典と根拠

ORDレコード
ord-16b8d96509494fc685582f67e77bc1c8
出典データセット
uspto-grants-2006_08
特許番号
US07090953B2

関連ノート

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