化工社化工社 化学情報印刷レポート · 研究参考用
Hydrazine hydrate (1:1) → 3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-5-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 反応物 | Ethyl 3-oxo-3-(pyridin-3-yl)propanoate | HCID 222197 | — |
| 生成物 | 3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-5-one | HCID 12448383 | 50% |
反応手順
The starting material was prepared using an analogous procedure to that described in Example 9. Ethyl-2-(3-pyridylcarbonyl)acetate (1 g, 5.18 mmol) was treated with hydrazine hydrate (251 μl, 5.2 mmol) to give 3-(3-pyridyl)-4,5-dihydro-1H-pyrazol-5-one (413 mg, 50%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07262201B1 |
| 出典データセット | uspto-grants-2007_08 |
| ORD ID | ord-e6da0555092e4373938afa6d5a060041 |
| 出典メモ | uspto-grants-2007_08 |