関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-Methylbenzoic acid | HCID 8373 | — |
| 反応物 | Chlorosulfonic acid | HCID 24638 | — |
| 生成物 | 5-(Chlorosulfonyl)-2-methylbenzoic acid | HCID 308449 | 78% |
反応手順
A mixture of o-toluic acid (15 g, 0.11 mol) and chlorosulfonic acid (30 ml) was heated at 100° C. under nitrogen for 2.5 h. The reaction mixture was then poured onto ice (500 ml) and the resulting precipitate was filtered, yielding the title compound as an off-white solid (20 g, 78% yield). MP 151–155° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07262318B2 |
|---|
| 出典データセット | uspto-grants-2007_08 |
|---|
| ORD ID | ord-d3765ec8103243a7987162440440850c |
|---|
| 出典メモ | uspto-grants-2007_08 |
|---|
