Crotonaldehyde → alpha-(4-Difluoromethoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile
反応式
[F:1][CH:2]([F:24])[O:3][C:4]1[CH:9]=[CH:8][C:7]([CH:10]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([S:20]([CH3:23])(=O)=O)=[CH:16][CH:15]=2)[C:11]#[N:12])=[CH:6][CH:5]=1.C(=O)/C=C/C>>[F:24][CH:2]([F:1])[O:3][C:4]1[CH:5]=[CH:6][C:7]([CH:10]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([S:20][CH3:23])=[CH:16][CH:15]=2)[C:11]#[N:12])=[CH:8][CH:9]=1参加物
3
実験手順
Following a procedure similar to that described in Example 1(iii), but using α-(4-difluoromethoxyphenyl)-α-(4-methylsulfonylanilino)acetonitrile [prepared as described in step (ii) above] and crotonaldehyde as starting materials, the title compound was obtained as a white powder (yield 31%), melting at 98-99° C.
出典と根拠
- ORDレコード
- ord-2aebb45d1c4140a6b49f0659aa90cf3d
- 出典データセット
- uspto-grants-2006_12
- 特許番号
- USRE039420E1
反応ノート
読み込み中…