Triethylamine → N'-{2-Chloro-5-[5-(3-chlorothiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenyl}-N,N-diethyl-ethane-1,2-diamine

関与物質

反応手順

From 2-chloro-5-[5-(3-chlorothiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenylamine (0.100 g, 0.320 mmol), anhydrous EtOH (1.3 mL), 2-bromo-N,N-diethylethylamine.HBr (0.334 g, 1.28 mmol) and Et3N (0.230 mL, 1.60 mmol) was obtained 0.006 g (5%) of the title compound as a white solid. 1H NMR (acetone-d6): 8.08 (d, 1H, J=5.5 Hz), 7.48–7.37 (m, 3H), 7.34 (d, 1H, J=5.2 Hz), 2.82–2.80 (m, 4H), 2.62–2.58 (m, 4H), 1.07 (t, 6H, J=7.0 Hz).

情報源と証拠