化工社化工社 化学情報印刷レポート · 研究参考用
3-Aminobenzoic Acid → 3-Hydrazinobenzoic acid hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Aminobenzoic Acid | HCID 7419 | — |
| 反応物 | Stannous chloride dihydrate | HCID 61436 | — |
| 反応物 | Sodium Nitrite | HCID 23668193 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | 3-Hydrazinobenzoic acid hydrochloride | HCID 12891863 | — |
反応手順
To a solution (200 mL) of m-amino benzoic acid (200 g, 1.46 mol) in concentrated HCl was added an aqueous solution (250 mL) of NaNO2 (102 g, 1.46 mol) at 0° C. The reaction mixture was stirred for 1 h and a solution of SnCl2.2H2O (662 g, 2.92 mol) in concentrated HCl (2 L) was then added at 0° C., and the reaction stirred for an additional 2 h at RT. The precipitate was filtered and washed with ethanol and ether to yield 3-hydrazino-benzoic acid hydrochloride as a white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07144911B2 |
| 出典データセット | uspto-grants-2006_12 |
| ORD ID | ord-645793c269594b1e94d3122f95c70ae3 |
| 出典メモ | uspto-grants-2006_12 |