Ethylamine → 6-(Ethylamino)pyridine-3-carboxylic acid
反応式
Cl[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][N:3]=1.[CH2:11]([NH2:13])[CH3:12]>>[CH2:11]([NH:13][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][N:3]=1)[CH3:12]参加物
3
実験手順
This intermediate is prepared from 6-chloronicotinic acid and ethylamine by the same procedure as described for Example 35 step a). 1-Butanol was substituted for ethyl acetate for the extraction. Recrystallization (MeOH—CHCl3) yielded 0.53 g (50%).
後処理
- extraction1-Butanol was substituted for ethyl acetate for the extraction
- customRecrystallization (MeOH—CHCl3)
- customyielded 0.53 g (50%)
出典と根拠
- ORDレコード
- ord-6697125ae1594b3486cb3b9065703dba
- 出典データセット
- uspto-grants-2006_12
- 特許番号
- US07148243B2
反応ノート
読み込み中…