Pyridinium chloride → 6-Chloro-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-5-ol

HRID 858226

反応式

HRID 858226 の反応式
[Cl:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([NH:9][C:10](=O)[C:11]2[CH:16]=[CH:15][C:14]([OH:17])=[C:13]([F:18])[CH:12]=2)=[C:4]([OH:20])[CH:3]=1.Cl.N1C=CC=CC=1>>[Cl:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]2[N:9]=[C:10]([C:11]3[CH:16]=[CH:15][C:14]([OH:17])=[C:13]([F:18])[CH:12]=3)[O:20][C:4]=2[CH:3]=1

参加物

3

反応物 2

HCID 10176127Pyridinium chlorideHCID 21907381N-(4-Chloro-2,5-dihydroxyphenyl)-3-fluoro-4-hydroxybenzamide

生成物 1

HCID 1354932236-Chloro-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-5-ol

実験手順

The title compound was prepared in substantially the same manner as described in Example 1, step b, from N-(4-chloro-2,5-dihydroxyphenyl)-3-fluoro-4-hydroxybenzamide and pyridine hydrochloride and was obtained as a white solid, m.p. 258–260° C.; MS m/e 278 (M−H)+.

後処理

  1. customwas obtained as a white solid, m.p. 258–260° C.

出典と根拠

ORDレコード
ord-d5cc9c2a7d03448cba77f68b9451f418
出典データセット
uspto-grants-2006_12
特許番号
US07148247B2

関連ノート

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