化工社化工社 化学情報印刷レポート · 研究参考用
Methylamine → 2-(4-Bromo-phenyl)-N-methyl-isobutyramide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methylamine | HCID 6329 | — |
| 反応物 | Monoethyl malonate | HCID 70615 | — |
| 反応物 | (R)-4-bromo-alpha-methylbenzylamine | HCID 853000 | — |
| 反応物 | 2-(4-Bromophenyl)-2-methylpropanoic acid | HCID 10933679 | — |
| 生成物 | 2-(4-Bromo-phenyl)-N-methyl-isobutyramide | HCID 58762757 | 84% |
反応手順
The title compound was prepared as described in Step 1 of Example A(39), where 2-(4-bromophenyl)-2-methyl propionic acid was substituted for ethyl hydrogen malonate and methyl amine was substituted instead of (R)-(+)-1-(4-bromophenyl)ethylamine on that example. Yield 84%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07148226B2 |
| 出典データセット | uspto-grants-2006_12 |
| ORD ID | ord-a025f88052e6471dbade514643702c64 |
| 出典メモ | uspto-grants-2006_12 |